Anacura

Experience

  • Plasmid vaccines
  • Oligonucleotides
  • mRNA vaccines

Analytical solutions

  • Product characterization
  • Method development
  • Method validation
  • Release
  • Stability
  • Comparability
  • Consultancy

Testing capabilities

Characterization

  • Multiplex testing (8 colours) by FACS
  • Primer and probe design
  • Electrochemiluminescence (MSD)

Identity

  • Single/ multiple protein marker(s)
  • Absence of marker(s)
  • Protein secretion
  • Gene expression
  • Distribution by flow cytometry

Purity

  • Percentage of dead cells & undesired cells
  • Ratio viability
  • MHCII

Quantity

  • Cell viability
  • Cell count

Potency

  • Biomarkes
  • ELISA
  • Gene expression by RT-qPCR
  • Enzymatic assays
  • Flow cytometry
  • Mixed lymphocyte reaction (MLR) assay

General quality

  • Appearance
  • pH
  • Osmolality

Process related impurities & contaminants

  • Host-derived (HCPs, DNA)
  • Downstream/ cultured-derived
  • Residual solvents/ chemicals/ biochemical/ inorganic salts
  • Medium components
  • Mycoplasma
  • Sterility
  • Endotoxins

Meet our scientist